Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CASR | P41180 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ACP1 | P24666 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18609918 | 0.92 | LMNA (0.47) | SMN1; SMN2CASRLMNAHTTACP1 | |
| SCHEMBL18610127 | 0.90 | LMNA (0.42) | SMN1; SMN2CASRLMNAHTTACP1 | |
| SCHEMBL18610135 | 0.86 | ATM (0.41) | SMN1; SMN2CASRLMNAHTTACP1 | |
| SCHEMBL18610128 | 0.86 | SMN1; SMN2 (0.42) | SMN1; SMN2CASRLMNAHTTACP1 | |
| SCHEMBL18610315 | 0.85 | ROCK1 (0.42) | CASRLMNAHTTMAPTNPSR1 | |
| SCHEMBL18609943 | 0.84 | POLB (0.41) | CASRLMNAMAPTATM | |
| SCHEMBL18610032 | 0.78 | CASR (0.41) | SMN1; SMN2CASRLMNAHTTACP1 | |
| SCHEMBL18609917 | 0.76 | ROCK1 (0.44) | SMN1; SMN2CASRLMNAMAPTNPSR1 | |
| Hydrochloric Acid SCHEMBL18584811 | 0.76 | ROCK1 (0.43) | SMN1; SMN2CASRLMNAMAPTNPSR1 | |
| SCHEMBL18610129 | 0.75 | ROCK1 (0.38) | SMN1; SMN2LMNAHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017037616-A1 | ARYLALKYLAMINE COMPOUNDS AS CALCIUM SENSING RECEPTOR MODULATORS | LUPIN LIMITED (IN) | 2017-03-09 | — | — | WO | disclosed |