Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 5/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ACP1 | P24666 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18609947 | 0.94 | HSD17B1 (0.35) | CASRADORA3MAOBADORA2AADORA2B | |
| SCHEMBL18610031 | 0.88 | CASR (0.38) | CASRADORA3MAOBADORA2AADORA2B | |
| SCHEMBL18610128 | 0.85 | SMN1; SMN2 (0.42) | CASRADORA3MAOBADORA2AADORA2B | |
| SCHEMBL18609946 | 0.84 | PPARG (0.37) | ADORA3MAOBADORA2AADORA2BADORA1 | |
| SCHEMBL18584441 | 0.84 | PPARG (0.37) | ADORA3MAOBADORA2AADORA2BADORA1 | |
| SCHEMBL18610127 | 0.81 | LMNA (0.42) | CASRSMN1; SMN2LMNAHTTMMP13 | |
| SCHEMBL18610314 | 0.78 | SMN1; SMN2 (0.44) | CASRSMN1; SMN2LMNAHTTMMP13 | |
| SCHEMBL16548150 | 0.77 | CASR (0.40) | CASRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL17939841 | 0.77 | CASR (0.40) | CASRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL18609918 | 0.76 | LMNA (0.47) | CASRSMN1; SMN2LMNAHTTMMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017037616-A1 | ARYLALKYLAMINE COMPOUNDS AS CALCIUM SENSING RECEPTOR MODULATORS | LUPIN LIMITED (IN) | 2017-03-09 | — | — | WO | disclosed |