Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28445448 | 0.79 | ADRA2A (0.36) | ADRA2AADRA2BADRA2CPTGS1PTGS2 | |
| SCHEMBL28448168 | 0.76 | ADRA2A (0.33) | ADRA2AADRA2BADRA2CPTGS1KDM4E | |
| SCHEMBL29029662 | 0.75 | ADRA2A (0.37) | ADRA2AADRA2BADRA2CKDM4EPOLB | |
| SCHEMBL152241 | 0.73 | — | — | |
| SCHEMBL20289047 | 0.70 | — | — | |
| SCHEMBL14738172 | 0.70 | — | — | |
| SCHEMBL1126027 | 0.69 | — | — | |
| SCHEMBL19407492 | 0.69 | ADRA2A (0.32) | ADRA2AADRA2BADRA2CKDM4EPOLB | |
| SCHEMBL17443471 | 0.68 | ADRA2A (0.34) | ADRA2AADRA2BADRA2CKDM4EPOLB | |
| SCHEMBL11783291 | 0.68 | ADRA2A (0.49) | ADRA2AADRA2BADRA2CCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3347061-B1 | INJECTABLE MACROPOROUS HYDROGELS | ETH ZUERICH (CH) | 2021-05-19 | — | — | EP | disclosed |
| US-20180264176-A1 | INJECTABLE MACROPOROUS HYDROGELS | ETH ZURICH (CH) | 2018-09-20 | — | — | US | disclosed |
| EP-3347061-A1 | INJECTABLE MACROPOROUS HYDROGELS | ETH Zürich (CH) | 2018-07-18 | — | — | EP | disclosed |
| CN-107075115-A | A kind of method for preparing uniform high molecular weight ring imido ether polymer | 根特大学 | 2017-08-18 | — | — | CN | disclosed |
| WO-2017042301-A1 | INJECTABLE MACROPOROUS HYDROGELS | ETH Zürich (CH) | 2017-03-16 | — | — | WO | disclosed |