Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18614770 | 0.79 | ADRA2A (0.39) | ADRA2AADRA2BADRA2CKDM4EPOLB | |
| SCHEMBL14167280 | 0.78 | ADRA2A (0.35) | ADRA2AADRA2BADRA2CKDM4EPOLB | |
| SCHEMBL28485870 | 0.77 | ALDH1A1 (0.37) | ADRA2AADRA2BADRA2CMAPTALDH1A1 | |
| SCHEMBL30866976 | 0.71 | KDM4E (0.30) | KDM4EPOLBCYP3A4MAPTNFKB1 | |
| SCHEMBL29029662 | 0.71 | ADRA2A (0.37) | ADRA2AADRA2BADRA2CKDM4EPOLB | |
| SCHEMBL1079623 | 0.70 | — | — | |
| SCHEMBL466674 | 0.69 | ADRA2A (0.41) | ADRA2AADRA2BADRA2CCYP3A4TSHR | |
| SCHEMBL21351773 | 0.69 | ADRA2A (0.41) | ADRA2AADRA2BADRA2CCYP3A4TSHR | |
| SCHEMBL152241 | 0.69 | — | — | |
| SCHEMBL19407492 | 0.69 | ADRA2A (0.32) | ADRA2AADRA2BADRA2CKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107075115-B | Method for preparing uniform high-molar-mass cyclic imino ether polymer | 根特大学 | 2020-05-29 | — | — | CN | disclosed |