Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 5/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2128231 | 0.94 | PDK2 (0.35) | ALOX5DNMT1PDK2 | |
| SCHEMBL15505878 | 0.90 | PDK2 (0.36) | ALOX5GPR84PDK2KCNJ11 | |
| SCHEMBL18613008 | 0.81 | ALOX5 (0.33) | ALOX5HPGDCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL13152865 | 0.79 | ALOX5 (0.42) | ALOX5GPR84HPGDHSD17B10CYP1A2 | |
| SCHEMBL29294794 | 0.78 | PDK2 (0.40) | PDK2 | |
| SCHEMBL15870870 | 0.76 | MEN1 (0.43) | HPGDHSD17B10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL19152597 | 0.76 | ALOX5 (0.44) | ALOX5CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL2132427 | 0.76 | CYP2C9 (0.42) | ALOX5GPR84HPGDHSD17B10CYP1A2 | |
| SCHEMBL18103622 | 0.76 | CA12 (0.39) | DNMT1 | |
| SCHEMBL14063310 | 0.76 | HSD17B10 (0.45) | HPGDHSD17B10CYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11158816-B2 | 6,9,15,18-tetrahydro-s-indaceno[1,2-b:5,6-b′]difluorene derivatives and use thereof in electronic devices | MERCK PATENT GMBH (DE) | 2021-10-26 | — | — | US | disclosed |
| EP-3341349-B1 | 6,9,15,18-TETRAHYDRO-S-INDACENO[1,2-B:5,6-B']DIFLUORENE- DERIVATIVES AND THEIR USE IN ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-01-29 | — | — | EP | disclosed |
| WO-2017036574-A1 | 6,9,15,18-TETRAHYDRO-S-INDACENO[1,2-B:5,6-B']DIFLUORENE DERIVATIVES AND USE THEREOF IN ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2017-03-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11158816-B2 | 6,9,15,18-tetrahydro-s-indaceno[1,2-b:5,6-b′]difluorene derivatives and use thereof in electronic devices | INF2, ETFB, INTS9 | ALOX5 957/4885GPR84 4160/4885HPGD 565/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.