Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 20/20 | 0.72 |
| ▸ | MERTK | Q12866 | 20/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18579986 | 0.84 | AXL (1.00) | AXLMERTK | |
| SCHEMBL20935619 | 0.81 | AXL (0.71) | AXLMERTK | |
| SCHEMBL21779384 | 0.78 | MERTK (0.60) | AXLMERTK | |
| SCHEMBL18615819 | 0.72 | AXL (0.72) | AXLMERTK | |
| SCHEMBL18580488 | 0.71 | MERTK (1.00) | AXLMERTK | |
| SCHEMBL18580034 | 0.71 | MERTK (1.00) | AXLMERTK | |
| SCHEMBL18580487 | 0.71 | MERTK (1.00) | AXLMERTK | |
| SCHEMBL18579877 | 0.70 | AXL (1.00) | AXLMERTK | |
| SCHEMBL18580401 | 0.70 | AXL (1.00) | AXLMERTK | |
| SCHEMBL18580207 | 0.68 | AXL (1.00) | AXLMERTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017039331-A1 | HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS | DONG-A SOCIO HOLDINGS CO., LTD. (KR) | 2017-03-09 | — | — | WO | disclosed |