Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 20/20 | 0.60 |
| ▸ | AXL | P30530 | 19/20 | 0.60 |
| ▸ | MET | P08581 | 1/20 | 0.59 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18615803 | 0.83 | MERTK (0.86) | MERTKAXLMETTYRO3 | |
| SCHEMBL18591582 | 0.83 | MERTK (0.86) | MERTKAXLMETTYRO3 | |
| SCHEMBL18615634 | 0.78 | AXL (0.72) | MERTKAXL | |
| SCHEMBL18615819 | 0.78 | AXL (0.72) | MERTKAXLTYRO3 | |
| SCHEMBL18580006 | 0.75 | MERTK (1.00) | MERTKAXLMETTYRO3 | |
| SCHEMBL18580007 | 0.75 | MERTK (1.00) | MERTKAXLMETTYRO3 | |
| SCHEMBL18580009 | 0.75 | MERTK (1.00) | MERTKAXLMETTYRO3 | |
| SCHEMBL18580428 | 0.75 | MERTK (1.00) | MERTKAXLMETTYRO3 | |
| SCHEMBL18579553 | 0.74 | MERTK (1.00) | MERTKAXLMETTYRO3 | |
| SCHEMBL18616157 | 0.74 | MERTK (1.00) | MERTKAXLMETTYRO3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3344613-B1 | HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS | DONG A SOCIO HOLDINGS CO LTD (KR) | 2020-03-04 | — | — | EP | disclosed |