Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 19/20 | 0.72 |
| ▸ | MERTK | Q12866 | 19/20 | 0.72 |
| ▸ | FLT3 | P36888 | 1/20 | 0.61 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18580176 | 0.84 | MERTK (1.00) | AXLMERTKFLT3TYRO3 | |
| SCHEMBL18579696 | 0.82 | AXL (0.97) | AXLMERTKFLT3TYRO3 | |
| SCHEMBL18579849 | 0.80 | AXL (0.94) | AXLMERTKFLT3TYRO3 | |
| SCHEMBL18580177 | 0.78 | AXL (0.90) | AXLMERTKFLT3TYRO3 | |
| SCHEMBL18579906 | 0.78 | AXL (0.86) | AXLMERTKFLT3TYRO3 | |
| SCHEMBL21779384 | 0.78 | MERTK (0.60) | AXLMERTKTYRO3 | |
| SCHEMBL18591608 | 0.78 | AXL (0.88) | AXLMERTKFLT3TYRO3 | |
| SCHEMBL18580382 | 0.78 | AXL (0.88) | AXLMERTKFLT3TYRO3 | |
| SCHEMBL18580571 | 0.77 | AXL (0.87) | AXLMERTKFLT3TYRO3 | |
| SCHEMBL18616290 | 0.77 | AXL (0.87) | AXLMERTKFLT3TYRO3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3344613-B1 | HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS | DONG A SOCIO HOLDINGS CO LTD (KR) | 2020-03-04 | — | — | EP | disclosed |
| WO-2017039331-A1 | HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS | DONG-A SOCIO HOLDINGS CO., LTD. (KR) | 2017-03-09 | — | — | WO | disclosed |