Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 6/20 | 0.42 |
| ▸ | CTSS | P25774 | 8/20 | 0.38 |
| ▸ | CTSK | P43235 | 3/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 8/20 | 0.37 |
| ▸ | CTSB | P07858 | 7/20 | 0.36 |
| ▸ | TACR2 | P21452 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23810263 | 0.92 | CTSS (0.35) | CTSLCTSSCTSKCACNA1HCTSB | |
| SCHEMBL23810318 | 0.91 | CTSL (0.41) | CTSLCTSSCTSKCTSBTACR2 | |
| SCHEMBL18616610 | 0.90 | CTSL (0.40) | CTSLCTSSCTSKCTSBTACR2 | |
| SCHEMBL18616609 | 0.88 | CTSL (0.45) | CTSLCTSSCTSKCTSBTACR2 | |
| SCHEMBL18616834 | 0.88 | CTSL (0.45) | CTSLCTSSCTSKCTSBTACR2 | |
| SCHEMBL18615883 | 0.88 | CTSL (0.45) | CTSLCTSSCTSKCTSBTACR2 | |
| SCHEMBL18615885 | 0.88 | CTSL (0.44) | CTSLCTSSCTSKCACNA1HCTSB | |
| SCHEMBL23810272 | 0.85 | CTSS (0.34) | CTSLCTSSCTSKCACNA1HCTSB | |
| SCHEMBL20341812 | 0.85 | CACNA1H (0.33) | CTSSCTSKCACNA1HCTSB | |
| SCHEMBL18615930 | 0.85 | CTSL (0.46) | CTSLCTSSCTSKCTSBTACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3342765-B1 | CATHEPSIN K INHIBITOR AND APPLICATION THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2021-09-15 | — | — | EP | disclosed |
| EP-3342765-A1 | CATHEPSIN K INHIBITOR AND APPLICATION THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2018-07-04 | — | — | EP | disclosed |
| WO-2017036357-A1 | CATHEPSIN K INHIBITOR AND APPLICATION THEREOF | 广东东阳光药业有限公司 | 2017-03-09 | — | — | WO | disclosed |