Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 12/20 | 0.46 |
| ▸ | CTSS | P25774 | 12/20 | 0.40 |
| ▸ | CTSK | P43235 | 8/20 | 0.40 |
| ▸ | CTSB | P07858 | 10/20 | 0.37 |
| ▸ | TACR2 | P21452 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18615954 | 0.91 | CTSL (0.38) | CTSLCTSSCTSKCTSBCA1 | |
| SCHEMBL20335433 | 0.82 | CTSL (0.52) | CTSLCTSSCTSKCTSBTACR2 | |
| SCHEMBL20335396 | 0.82 | CTSL (0.52) | CTSLCTSSCTSKCTSBTACR2 | |
| SCHEMBL28425902 | 0.82 | CTSL (0.63) | CTSLCTSSCTSKCTSBCA1 | |
| SCHEMBL28421516 | 0.82 | CTSL (0.63) | CTSLCTSSCTSKCTSBCA1 | |
| SCHEMBL23810312 | 0.80 | CTSL (0.49) | CTSLCTSSCTSKCTSBTACR2 | |
| SCHEMBL23810246 | 0.80 | CTSL (0.45) | CTSLCTSSCTSKCTSBTACR2 | |
| SCHEMBL23810255 | 0.80 | CTSL (0.45) | CTSLCTSSCTSKCTSBTACR2 | |
| SCHEMBL18615930 | 0.79 | CTSL (0.46) | CTSLCTSSCTSKCTSBTACR2 | |
| SCHEMBL18616651 | 0.78 | CTSL (0.45) | CTSLCTSSCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3342765-B1 | CATHEPSIN K INHIBITOR AND APPLICATION THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2021-09-15 | — | — | EP | disclosed |
| EP-3342765-B1 | CATHEPSIN K INHIBITOR AND APPLICATION THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2021-09-15 | — | — | EP | disclosed |
| CN-107922315-B | Cathepsin K inhibitors and uses thereof | 广东东阳光药业有限公司 | 2021-03-26 | — | — | CN | disclosed |
| EP-3342765-A1 | CATHEPSIN K INHIBITOR AND APPLICATION THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2018-07-04 | — | — | EP | disclosed |
| EP-3342765-A1 | CATHEPSIN K INHIBITOR AND APPLICATION THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2018-07-04 | — | — | EP | disclosed |
| WO-2017036357-A1 | CATHEPSIN K INHIBITOR AND APPLICATION THEREOF | 广东东阳光药业有限公司 | 2017-03-09 | — | — | WO | disclosed |