Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 14/20 | 0.63 |
| ▸ | CTSB | P07858 | 13/20 | 0.48 |
| ▸ | CTSS | P25774 | 12/20 | 0.48 |
| ▸ | CTSK | P43235 | 6/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28421516 | 1.00 | CTSL (0.63) | CTSLCTSBCTSSCTSKCA1 | |
| SCHEMBL18615903 | 0.82 | CTSL (0.46) | CTSLCTSBCTSSCTSKCA1 | |
| SCHEMBL28421665 | 0.79 | CTSL (0.74) | CTSLCTSBCTSSCTSKCTSD | |
| SCHEMBL28424711 | 0.79 | CTSL (0.74) | CTSLCTSBCTSSCTSKCTSD | |
| SCHEMBL6184450 | 0.75 | CTSL (0.72) | CTSLCTSBCTSSCTSKCTSD | |
| SCHEMBL28427138 | 0.75 | CTSL (0.64) | CTSLCTSBCTSSCTSK | |
| SCHEMBL18615954 | 0.73 | CTSL (0.38) | CTSLCTSBCTSSCTSKCA1 | |
| SCHEMBL22439042 | 0.71 | CA1 (0.41) | CTSLCTSBCTSSCA1CA2 | |
| SCHEMBL16760259 | 0.70 | LRRK2 (0.37) | CTSLCTSBCTSSCTSKCA1 | |
| SCHEMBL23693711 | 0.70 | CTSL (0.56) | CTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106928113-B | Cathepsin K inhibitors and uses thereof | 广东东阳光药业有限公司 | 2020-07-07 | — | — | CN | disclosed |