Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 13/20 | 0.45 |
| ▸ | CTSS | P25774 | 14/20 | 0.39 |
| ▸ | CTSK | P43235 | 9/20 | 0.39 |
| ▸ | CTSB | P07858 | 11/20 | 0.38 |
| ▸ | TACR2 | P21452 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18616651 | 0.93 | CTSL (0.45) | CTSLCTSSCTSKCTSB | |
| SCHEMBL18616546 | 0.93 | CTSL (0.45) | CTSLCTSSCTSKCTSB | |
| SCHEMBL18615881 | 0.92 | CTSL (0.46) | CTSLCTSSCTSKCTSB | |
| SCHEMBL18615943 | 0.89 | CTSL (0.44) | CTSLCTSSCTSKCTSBTACR2 | |
| SCHEMBL23810312 | 0.88 | CTSL (0.49) | CTSLCTSSCTSKCTSBTACR2 | |
| SCHEMBL23810246 | 0.88 | CTSL (0.45) | CTSLCTSSCTSKCTSBTACR2 | |
| SCHEMBL23810255 | 0.88 | CTSL (0.45) | CTSLCTSSCTSKCTSBTACR2 | |
| SCHEMBL18616591 | 0.87 | CTSL (0.46) | CTSLCTSSCTSKCTSBTACR2 | |
| SCHEMBL18615992 | 0.86 | CTSL (0.40) | CTSLCTSSCTSKCTSB | |
| SCHEMBL28656923 | 0.86 | CTSL (0.45) | CTSLCTSSCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017036357-A1 | CATHEPSIN K INHIBITOR AND APPLICATION THEREOF | 广东东阳光药业有限公司 | 2017-03-09 | — | — | WO | disclosed |