Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 9/20 | 0.45 |
| ▸ | CTSB | P07858 | 15/20 | 0.39 |
| ▸ | CTSS | P25774 | 13/20 | 0.39 |
| ▸ | CTSK | P43235 | 12/20 | 0.39 |
| ▸ | CTSV | O60911 | 1/20 | 0.39 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18616546 | 0.93 | CTSL (0.45) | CTSLCTSBCTSSCTSKCTSV | |
| SCHEMBL18616651 | 0.93 | CTSL (0.45) | CTSLCTSBCTSSCTSKCTSV | |
| SCHEMBL18615881 | 0.92 | CTSL (0.46) | CTSLCTSBCTSSCTSKCTSV | |
| SCHEMBL28644393 | 0.88 | CTSL (0.42) | CTSLCTSBCTSSCTSKCTSV | |
| SCHEMBL18615940 | 0.86 | CTSL (0.45) | CTSLCTSBCTSSCTSK | |
| SCHEMBL18616591 | 0.85 | CTSL (0.46) | CTSLCTSBCTSSCTSKCTSV | |
| SCHEMBL18616590 | 0.85 | CTSC (0.41) | CTSLCTSBCTSSCTSKCTSV | |
| SCHEMBL18615992 | 0.84 | CTSL (0.40) | CTSLCTSBCTSSCTSKCTSV | |
| SCHEMBL18615942 | 0.84 | CTSK (0.41) | CTSLCTSBCTSSCTSKCTSV | |
| SCHEMBL18616543 | 0.84 | CTSL (0.43) | CTSLCTSBCTSSCTSKCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106478564-B | Cathepsin K inhibitors and uses thereof | 广东东阳光药业有限公司 | 2021-11-12 | — | — | CN | disclosed |