Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 5/20 | 0.50 |
| ▸ | MERTK | Q12866 | 5/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 5/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | BMPR1B | O00238 | 3/20 | 0.44 |
| ▸ | BMPR1A | P36894 | 3/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.44 |
| ▸ | ACVRL1 | P37023 | 3/20 | 0.44 |
| ▸ | ACVR1 | Q04771 | 3/20 | 0.44 |
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21779420 | 0.89 | AXL (0.52) | AXLMERTKMAP4K4KCNH2BMPR1B | |
| SCHEMBL18615708 | 0.78 | AXL (0.62) | AXLMERTKMAP4K4BMPR1BBMPR1A | |
| SCHEMBL8807848 | 0.73 | HRH3 (0.62) | MAP4K4KCNH2PARP1POLBALDH1A1 | |
| SCHEMBL14202576 | 0.71 | PRMT6 (0.57) | MAP4K4KCNH2PARP1POLBALDH1A1 | |
| SCHEMBL3141112 | 0.70 | KCNH2 (0.55) | MAP4K4KCNH2PARP1POLBALDH1A1 | |
| SCHEMBL11509945 | 0.70 | ALDH1A1 (0.68) | KCNH2PARP1POLBALDH1A1KDM4E | |
| SCHEMBL9252404 | 0.70 | ALDH1A1 (0.68) | KCNH2PARP1POLBALDH1A1KDM4E | |
| SCHEMBL3461772 | 0.69 | PIK3CD (0.57) | MAP4K4ACVR1 | |
| SCHEMBL8811228 | 0.69 | IRAK1 (0.51) | AXLMERTKMAP4K4KCNH2PARP1 | |
| SCHEMBL22306745 | 0.68 | MAP4K4 (0.57) | MAP4K4KCNH2PARP1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017039331-A1 | HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS | DONG-A SOCIO HOLDINGS CO., LTD. (KR) | 2017-03-09 | — | — | WO | disclosed |