Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1647150 | 0.85 | MEN1 (0.52) | MEN1KMT2ALMNATDP1THRB | |
| SCHEMBL24250390 | 0.83 | MEN1 (0.44) | MEN1KMT2ALMNATDP1THRB | |
| SCHEMBL19277030 | 0.81 | MEN1 (0.39) | MEN1KMT2ALMNATDP1THRB | |
| SCHEMBL18678765 | 0.79 | LMNA (0.40) | MEN1KMT2ALMNATDP1THRB | |
| SCHEMBL28985637 | 0.79 | POLB (0.60) | MEN1KMT2ALMNAPOLBHTT | |
| SCHEMBL22434096 | 0.79 | MEN1 (0.41) | MEN1KMT2ALMNATDP1THRB | |
| SCHEMBL24810740 | 0.79 | MEN1 (0.40) | MEN1KMT2ALMNATDP1THRB | |
| SCHEMBL19676845 | 0.79 | ADRA1D (0.42) | MEN1KMT2ALMNATDP1THRB | |
| SCHEMBL22475453 | 0.77 | MEN1 (0.39) | MEN1KMT2ALMNATDP1THRB | |
| SCHEMBL20777519 | 0.77 | HPGD (0.43) | MEN1KMT2ALMNATDP1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017040766-A1 | ANTI-VIRAL TETRAHYDROFURANE DERIVATIVES | ABBVIE INC. (US) | 2017-03-09 | — | — | WO | disclosed |