Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 6/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 2/20 | 0.40 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18549838 | 0.87 | NR4A2 (0.47) | NR4A2MAOBPARP10ALKBH1 | |
| SCHEMBL18550468 | 0.85 | S1PR5 (0.51) | NR4A2MAOBPARP10ALKBH1 | |
| SCHEMBL18550316 | 0.83 | S1PR5 (0.58) | NR4A2MAOBPARP10ALKBH1 | |
| SCHEMBL18550286 | 0.82 | S1PR5 (0.47) | NR4A2MAOB | |
| SCHEMBL18550038 | 0.82 | S1PR5 (0.49) | NR4A2MAOBMAOA | |
| SCHEMBL18550008 | 0.81 | S1PR5 (0.42) | NR4A2MAOBPARP10BTK | |
| SCHEMBL18617643 | 0.80 | JAK1 (0.40) | PRMT5 | |
| SCHEMBL18550306 | 0.79 | S1PR5 (0.58) | NR4A2MAOBPARP10ALKBH1MAOA | |
| SCHEMBL18550139 | 0.79 | MAPT (0.49) | NR4A2MAOBPARP10BTK | |
| SCHEMBL18549883 | 0.78 | ITGB3 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017036978-A1 | FUSED HETEROCYCLIC COMPOUNDS AS S1P MODULATORS | ABBVIE INC. (US) | 2017-03-09 | — | — | WO | disclosed |