Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18617070 | 0.89 | S1PR5 (0.36) | MAPTS1PR5 | |
| SCHEMBL18550156 | 0.88 | S1PR5 (0.47) | JAK1CYP19A1CYP11B1CYP11B2ENPP2 | |
| SCHEMBL18617641 | 0.85 | S1PR5 (0.39) | MAPTS1PR5 | |
| SCHEMBL18617598 | 0.81 | TP53 (0.40) | MAPTPRMT5WDR77S1PR5 | |
| SCHEMBL18617044 | 0.80 | NR4A2 (0.41) | PRMT5 | |
| SCHEMBL18616831 | 0.79 | GPR119 (0.46) | MAPTS1PR5 | |
| SCHEMBL18549934 | 0.79 | S1PR5 (0.47) | MRGPRX4S1PR5 | |
| SCHEMBL18550232 | 0.78 | S1PR5 (0.49) | CYP19A1CYP11B1CYP11B2MRGPRX4S1PR5 | |
| SCHEMBL18617074 | 0.78 | S1PR5 (0.43) | PRMT5WDR77S1PR5 | |
| SCHEMBL18549882 | 0.77 | FFAR1 (0.51) | MRGPRX4S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017036978-A1 | FUSED HETEROCYCLIC COMPOUNDS AS S1P MODULATORS | ABBVIE INC. (US) | 2017-03-09 | — | — | WO | disclosed |