Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 7/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18618135 | 0.88 | PPARD (0.48) | PPARDPPARAS1PR1S1PR3NQO2 | |
| SCHEMBL18617329 | 0.87 | PPARD (0.44) | PPARDPPARAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL20671959 | 0.87 | S1PR1 (0.44) | PPARDS1PR1S1PR3NQO2MTNR1A | |
| SCHEMBL18616751 | 0.80 | S1PR1 (0.49) | PPARDPPARAS1PR1S1PR3ALDH1A1 | |
| SCHEMBL18616585 | 0.74 | PPARD (0.44) | PPARDSMN1; SMN2TSHR | |
| SCHEMBL20672040 | 0.74 | HTR6 (0.42) | PPARD | |
| SCHEMBL13462885 | 0.73 | KDM4E (0.56) | PPARDKDM4EALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL15295402 | 0.72 | ALDH1A1 (0.65) | KDM4EALDH1A1SMN1; SMN2TSHRMAPK1 | |
| SCHEMBL28306905 | 0.72 | ALDH1A1 (0.54) | KDM4EALDH1A1SMN1; SMN2TSHRMAPK1 | |
| SCHEMBL8057463 | 0.71 | ALDH1A1 (0.59) | KDM4EALDH1A1SMN1; SMN2TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017040449-A1 | TRIAZOLOPYRIDINE INHIBITORS OF MYELOPEROXIDASE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-03-09 | — | — | WO | disclosed |