Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.43 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.38 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.36 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 3/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20671890 | 0.89 | DRD2 (0.42) | TLR9TLR8TLR7SSTR4HTR2C | |
| SCHEMBL18618107 | 0.86 | CHRNB4 (0.50) | TLR9TLR8TLR7SSTR4SLC5A1 | |
| SCHEMBL18617804 | 0.84 | SLC5A1 (0.37) | SSTR4SLC5A1SLC5A2HTR2CCHRNB4 | |
| SCHEMBL17308329 | 0.79 | HTR2C (0.50) | HTR2C | |
| SCHEMBL24394293 | 0.76 | KDM1A (0.50) | HTR2CMAPTPKMSLC6A2SLC6A4 | |
| SCHEMBL24907357 | 0.76 | KDM1A (0.50) | HTR2CMAPTPKMSLC6A2SLC6A4 | |
| SCHEMBL3127083 | 0.76 | KDM1A (0.50) | HTR2CMAPTPKMSLC6A2SLC6A4 | |
| SCHEMBL23284411 | 0.76 | KDM1A (0.50) | HTR2CMAPTPKMSLC6A2SLC6A4 | |
| SCHEMBL3121885 | 0.76 | KDM1A (0.50) | HTR2CMAPTPKMSLC6A2SLC6A4 | |
| SCHEMBL3126247 | 0.76 | KDM1A (0.50) | HTR2CMAPTPKMSLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017040449-A1 | TRIAZOLOPYRIDINE INHIBITORS OF MYELOPEROXIDASE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-03-09 | — | — | WO | disclosed |