Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A1 | P13866 | 1/20 | 0.37 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.37 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.37 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 3/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | EED | O75530 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20671885 | 0.89 | DRD2 (0.43) | SSTR1SSTR4HTR2CCHRNB4CHRNA3 | |
| SCHEMBL18617817 | 0.84 | TLR9 (0.43) | SLC5A1SLC5A2SSTR4HTR2CCHRNB4 | |
| SCHEMBL13439513 | 0.84 | MAPT (0.37) | SSTR1SSTR4HTR2CMAPTPKM | |
| SCHEMBL13439512 | 0.84 | MAPT (0.37) | SSTR1SSTR4HTR2CMAPTPKM | |
| SCHEMBL30228264 | 0.83 | P2RY14 (0.37) | SSTR1SSTR4HTR2CCHRNB4CHRNA3 | |
| SCHEMBL13646153 | 0.82 | SSTR1 (0.40) | SSTR1SSTR4MAPTPKM | |
| SCHEMBL13646152 | 0.82 | SSTR1 (0.40) | SSTR1SSTR4MAPTPKM | |
| SCHEMBL13646150 | 0.82 | SSTR1 (0.40) | SSTR1SSTR4MAPTPKM | |
| SCHEMBL13646151 | 0.82 | SSTR1 (0.40) | SSTR1SSTR4MAPTPKM | |
| SCHEMBL17308329 | 0.80 | HTR2C (0.50) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017040449-A1 | TRIAZOLOPYRIDINE INHIBITORS OF MYELOPEROXIDASE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-03-09 | — | — | WO | disclosed |