SCHEMBL18618917

SCHEMBL18618917

c1ccc(-n2c3ccccc3c3cc4c5ccc6oc7ccccc7c6c5n(-c5ccccc5)c4cc32)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.47
ATM Q13315 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
ALDH1A1 P00352 6/20 0.36
SMN1; SMN2 Q16637 4/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
LMNA P02545 2/20 0.36
POLB P06746 1/20 0.36
TSHR P16473 1/20 0.36
BRCA1 P38398 1/20 0.36
HSD17B10 Q99714 1/20 0.36
CA9 Q16790 3/20 0.34
CA12 O43570 2/20 0.34
RXFP1 Q9HBX9 2/20 0.33
PPARG P37231 1/20 0.33
NR2E3 Q9Y5X4 1/20 0.33
NCOR2 Q9Y618 1/20 0.33
MAPT P10636 2/20 0.33
HPGD P15428 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18620228 0.96 KDM4E (0.49) KDM4EATML3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL19342721 0.95 L3MBTL1 (0.43) KDM4EATML3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL18868243 0.92 L3MBTL1 (0.40) KDM4EATML3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL17300006 0.92 L3MBTL1 (0.40) KDM4EATML3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL17299704 0.92 L3MBTL1 (0.40) KDM4EATML3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL17246088 0.92 KDM4E (0.52) KDM4EATML3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL17246163 0.91 L3MBTL1 (0.46) KDM4EATML3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL18868235 0.91 L3MBTL1 (0.39) KDM4EATML3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL18868237 0.91 KDM4E (0.39) KDM4EATML3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL17300004 0.91 L3MBTL1 (0.39) KDM4EATML3MBTL1ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10703762-B2 Compound, material for organic electroluminescence device, organic electroluminescence device and electronic apparatus IDEMITSU KOSAN CO., LTD. (JP) 2020-07-07 US disclosed
US-10319918-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD (KR) 2019-06-11 US disclosed
US-20170352814-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2017-12-07 US disclosed
US-20170352814-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2017-12-07 US disclosed
US-9768394-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2017-09-19 US disclosed
US-9768394-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2017-09-19 US disclosed
US-20170141326-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2017-05-18 US disclosed
US-20170141326-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2017-05-18 US disclosed
WO-2017038728-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT MATERIAL, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE 出光興産株式会社 2017-03-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10319918-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same OR10J3, VDAC1, ICOSLG KDM4E 652/4885ATM 1420/4885L3MBTL1 315/4885
US-20170352814-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME OR10J3, VDAC1, ICOSLG KDM4E 652/4885ATM 1420/4885L3MBTL1 315/4885
US-10703762-B2 Compound, material for organic electroluminescence device, organic electroluminescence device and electronic apparatus PIEZO1, OR10J3, EPCAM KDM4E 3529/4885ATM 1283/4885L3MBTL1 2738/4885
US-20170141326-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME OR10J3, VDAC1, ICOSLG KDM4E 652/4885ATM 1420/4885L3MBTL1 315/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.