Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 4/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.42 |
| ▸ | DPP4 | P27487 | 2/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
| ▸ | PREP | P48147 | 2/20 | 0.40 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22209464 | 0.90 | MALT1 (0.57) | MALT1OPRM1OPRK1DPP4DPP8 | |
| SCHEMBL22209365 | 0.89 | MALT1 (0.64) | MALT1CMA1EPHA2 | |
| SCHEMBL22811073 | 0.89 | MALT1 (0.64) | MALT1CMA1EPHA2 | |
| SCHEMBL18619572 | 0.89 | MALT1 (0.64) | MALT1CMA1EPHA2 | |
| SCHEMBL18621052 | 0.89 | MALT1 (0.64) | MALT1CMA1EPHA2 | |
| SCHEMBL18619638 | 0.88 | MALT1 (0.57) | MALT1OPRM1OPRK1DPP4DPP8 | |
| SCHEMBL18619636 | 0.87 | MALT1 (0.55) | MALT1OPRM1OPRK1DPP4DPP8 | |
| SCHEMBL18619626 | 0.87 | MALT1 (0.59) | MALT1DPP4DPP8DPP9DPP7 | |
| SCHEMBL22209378 | 0.87 | MALT1 (0.61) | MALT1DPP4DPP8DPP9DPP7 | |
| SCHEMBL18619570 | 0.87 | MALT1 (0.55) | MALT1OPRM1OPRK1DPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017040304-A1 | MALT1 INHIBITORS AND USES THEREOF | CORNELL UNIVERSITY (US) | 2017-03-09 | — | — | WO | disclosed |