⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5669163 | 0.87 | — | — | |
| SCHEMBL14970377 | 0.87 | — | — | |
| SCHEMBL48989 | 0.87 | — | — | |
| SCHEMBL20244940 | 0.85 | — | — | |
| SCHEMBL21338510 | 0.85 | — | — | |
| SCHEMBL13397296 | 0.85 | CRAT (0.42) | — | |
| SCHEMBL2548083 | 0.85 | — | — | |
| SCHEMBL12807817 | 0.85 | — | — | |
| SCHEMBL11073459 | 0.83 | ALDH1A1 (0.52) | — | |
| SCHEMBL14294441 | 0.83 | ALDH1A1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220281-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF COINFECTION WITH EIMERIA AND CLOSTRIDIUM | CAN TECHNOLOGIES, INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| EP-4234634-A2 | MODIFIED CYANINE DYES AND CONJUGATES THEREOF | Bracco Imaging SPA (IT) | 2023-08-30 | — | — | EP | disclosed |
| US-20230234978-A1 | NUCLEIC ACID-POLYPEPTIDE COMPOSITIONS AND USES THEREOF | Atrium Therapeutics, Inc. | 2023-07-27 | — | — | US | disclosed |
| US-20230234978-A1 | NUCLEIC ACID-POLYPEPTIDE COMPOSITIONS AND USES THEREOF | Atrium Therapeutics, Inc. | 2023-07-27 | — | — | US | disclosed |
| EP-3969063-B1 | MODIFIED CYANINE DYES AND CONJUGATES THEREOF | BRACCO IMAGING SPA (IT) | 2023-07-05 | — | — | EP | disclosed |
| WO-2023072974-A1 | TRICYCLIC HETEROCYCLES | MERCK PATENT GMBH (DE) | 2023-05-04 | — | — | WO | disclosed |
| US-11578090-B2 | Nucleic acid-polypeptide compositions and uses thereof | AVIDITY BIOSCIENCES, INC. (US) | 2023-02-14 | — | — | US | disclosed |
| US-20210363165-A1 | NITROXOLINE PRODRUG AND USE THEREOF | JIANGSU YAHONG MEDITECH CO., LTD. (CN) | 2021-11-25 | — | — | US | disclosed |
| CN-108530381-B | Method for preparing diamine derivative from amide ester | 上海科技大学 | 2021-09-21 | — | — | CN | disclosed |
| US-10869846-B2 | N-acetylcysteine amide (NAC amide) in the treatment of diseases and conditions associated with oxidative stress | SENTIENT LIFESCIENCES, INC. (US) | 2020-12-22 | — | — | US | disclosed |
| US-20050131016-A1 | Chemical compounds | ASTRAZENECA AB (SE) | 2005-06-16 | — | — | US | disclosed |
| EP-1485371-A2 | INDOLE AMIDE DERIVATIVES AND THEIR USE AS GLYCOGEN PHOSPHORYLASE INHIBITORS | AstraZeneca AB (SE) | 2004-12-15 | — | — | EP | disclosed |
| EP-1483270-A1 | HETEROCYCLIC AMIDE DERIVATIVES AS INHIBITORS OF GLYCOGEN PHOSPHORYLASE | Astrazeneca AB (SE) | 2004-12-08 | — | — | EP | disclosed |
| EP-1317459-B1 | BICYCLIC PYRROLYL AMIDES AS GLUCOGEN PHOSPHORYLASE INHIBITORS | ASTRAZENECA AB (SE) | 2004-04-07 | — | — | EP | disclosed |
| US-20030232875-A1 | Bicyclic pyrrolyl amides as glucogen phosphorylase inhibitors | ASTRAZENECA AB (SE) | 2003-12-18 | — | — | US | disclosed |
| WO-2003074513-A2 | INDOLE AMIDE DERIVATIVES AND THEIR USE AS GLYCOGEN PHOSPHORYLASE INHIBITORS | ASTRAZENECA AB (SE) | 2003-09-12 | — | — | WO | disclosed |
| WO-2003074532-A1 | HETEROCYCLIC AMIDE DERIVATIVES AS INHIBITORS OF GLYCOGEN PHOSPHORYLASE | ASTRAZENECA AB (SE) | 2003-09-12 | — | — | WO | disclosed |
| EP-1317459-A1 | BICYCLIC PYRROLYL AMIDES AS GLUCOGEN PHOSPHORYLASE INHIBITORS | AstraZeneca AB (SE) | 2003-06-11 | — | — | EP | disclosed |
| WO-2002020530-A1 | BICYCLIC PYRROLYL AMIDES AS GLUCOGEN PHOSPHORYLASE INHIBITORS | ASTRAZENECA AB (SE) | 2002-03-14 | — | — | WO | disclosed |
| WO-2001058848-A1 | A PROCESS FOR THE PURIFICATION OF 3-AMINO-1,2-PROPANEDIOL AND 2-AMINO-1,3-PROPANEDIOL | BRACCO IMAGING S.P.A. (IT) | 2001-08-16 | — | — | WO | disclosed |