Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.38 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | MPO | P05164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18620992 | 0.85 | MPO (0.50) | FNTAFNTBMPOMAPTSMN1; SMN2 | |
| SCHEMBL18619967 | 0.78 | MPO (0.42) | SGMS1SGMS2MPOALOX5APFEN1 | |
| SCHEMBL18585011 | 0.78 | MPO (0.36) | SGMS1SGMS2MPOMAPTSMN1; SMN2 | |
| SCHEMBL18585009 | 0.78 | MPO (0.36) | SGMS1SGMS2MPOMAPTSMN1; SMN2 | |
| SCHEMBL18621046 | 0.74 | AGPAT2 (0.41) | MAPTPOLBMEN1PKMKMT2A | |
| SCHEMBL18621117 | 0.72 | SCN1A (0.36) | MAPTMEN1KMT2A | |
| SCHEMBL18621051 | 0.72 | LNPEP (0.44) | SGMS1SGMS2MPOKCNN3ALOX5AP | |
| SCHEMBL18585182 | 0.70 | MPO (0.44) | SGMS1SGMS2MPOKCNN3ALOX5AP | |
| SCHEMBL20429918 | 0.67 | MPO (0.49) | MPOSMN1; SMN2TP53KCNN3GRIN2B | |
| Trifluoroacetic Acid SCHEMBL18585084 | 0.66 | LNPEP (0.50) | ALOX5APFEN1PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017040450-A1 | TRIAZOLOPYRIDINE INHIBITORS OF MYELOPEROXIDASE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-03-09 | — | — | WO | disclosed |