Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 3/20 | 0.41 |
| ▸ | PLAU | P00749 | 2/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13663688 | 0.88 | HSP90AA1 (0.38) | PLGPLAUF10KLKB1CYP1A2 | |
| SCHEMBL4431792 | 0.85 | PLG (0.41) | PLGPLAUF10KLKB1PTGS1 | |
| SCHEMBL18506897 | 0.85 | PLG (0.41) | PLGPLAUF10KLKB1PTGS1 | |
| SCHEMBL18545144 | 0.83 | PLG (0.41) | PLGPLAUF10KLKB1PTGS1 | |
| SCHEMBL4082092 | 0.81 | PLG (0.41) | PLGPLAUF10KLKB1PTGS1 | |
| SCHEMBL850468 | 0.79 | PLG (0.45) | PLGPLAUF10KLKB1CYP3A4 | |
| SCHEMBL8961190 | 0.79 | PLG (0.40) | PLGPLAUF10KLKB1PTGS1 | |
| SCHEMBL8529805 | 0.79 | PLG (0.39) | PLGPLAUF10KLKB1PTGS1 | |
| SCHEMBL8531015 | 0.77 | CYP1A2 (0.39) | PLGPLAUF10KLKB1PTGS1 | |
| SCHEMBL4530181 | 0.77 | PTGS1 (0.42) | PLGPLAUF10KLKB1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017040304-A1 | MALT1 INHIBITORS AND USES THEREOF | CORNELL UNIVERSITY (US) | 2017-03-09 | — | — | WO | disclosed |