Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 3/20 | 0.40 |
| ▸ | PLAU | P00749 | 2/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TTPA | P49638 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18506897 | 0.84 | PLG (0.41) | PLGPLAUF10KLKB1F2 | |
| SCHEMBL4428219 | 0.84 | PLG (0.41) | PLGPLAUF10KLKB1F2 | |
| SCHEMBL4426832 | 0.84 | PLG (0.41) | PLGPLAUF10KLKB1F2 | |
| SCHEMBL4437400 | 0.84 | PLG (0.41) | PLGPLAUF10KLKB1F2 | |
| SCHEMBL8961475 | 0.83 | PLG (0.42) | PLGPLAUF10KLKB1F2 | |
| SCHEMBL4438412 | 0.83 | PLG (0.40) | PLGPLAUF10KLKB1F2 | |
| SCHEMBL4428216 | 0.82 | PLG (0.40) | PLGPLAUF10KLKB1F2 | |
| SCHEMBL18586526 | 0.81 | PLG (0.39) | PLGPLAUF10KLKB1F2 | |
| SCHEMBL8961205 | 0.81 | HDAC3 (0.41) | PLGPLAUF10KLKB1F2 | |
| SCHEMBL4986565 | 0.80 | PLG (0.39) | PLGPLAUF10KLKB1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0693081-A1 | CYCLIC COMPOUNDS AND COMPOSITIONS WHICH INHIBIT BONE RESORPTION | Novartis AG (CH) | 1996-01-24 | — | — | EP | disclosed |
| WO-1994024153-A1 | CYCLIC COMPOUNDS AND COMPOSITIONS WHICH INHIBIT BONE RESORPTION | CIBA-GEIGY AG (CH) | 1994-10-27 | — | — | WO | disclosed |