Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3296809 | 0.78 | IDO1 (0.61) | IDO1TAAR1CHRM2CHRM1L3MBTL1 | |
| SCHEMBL1859749 | 0.78 | TAAR1 (0.37) | TAAR1CHRM2KMT2AMAPTALDH1A1 | |
| SCHEMBL1862209 | 0.75 | IDO1 (0.46) | IDO1TAAR1CHRM2CHRM1MEN1 | |
| SCHEMBL1861219 | 0.73 | IDO1 (0.43) | IDO1KMT2AL3MBTL1ALDH1A1ATM | |
| SCHEMBL1859772 | 0.72 | LTA4H (0.46) | IDO1MAPTALDH1A1ATMTSHR | |
| SCHEMBL4626572 | 0.71 | IDO1 (0.62) | IDO1TAAR1MEN1KMT2AL3MBTL1 | |
| SCHEMBL2351374 | 0.70 | MAPT (0.40) | MEN1KMT2AL3MBTL1HTTGAA | |
| SCHEMBL8611010 | 0.70 | KMT2A (0.54) | IDO1TAAR1CHRM2CHRM1MEN1 | |
| SCHEMBL22800045 | 0.70 | IDO1 (0.52) | IDO1TAAR1CHRM2CHRM1L3MBTL1 | |
| SCHEMBL8035410 | 0.70 | CNR2 (0.55) | IDO1TAAR1CHRM2CHRM1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7939509-B2 | Partial and full agonists of A1 adenosine receptors | GILEAD SCIENCES, INC. (US) | 2011-05-10 | — | — | US | disclosed |