Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15975676 | 0.90 | ALDH1A1 (0.35) | NPC1RAB9AALDH1A1DGAT1MAPK1 | |
| SCHEMBL14904688 | 0.89 | NPC1 (0.39) | NPC1RAB9AALDH1A1DGAT1NAMPT | |
| SCHEMBL16653197 | 0.81 | NPC1 (0.41) | NPC1RAB9AALDH1A1DGAT1NAMPT | |
| SCHEMBL4967348 | 0.81 | NPC1 (0.38) | NPC1RAB9AALDH1A1DGAT1NAMPT | |
| SCHEMBL14904618 | 0.80 | NPC1 (0.40) | NPC1RAB9ADGAT1NAMPTMAPK1 | |
| SCHEMBL14904700 | 0.80 | NPC1 (0.40) | NPC1RAB9AALDH1A1DGAT1NAMPT | |
| SCHEMBL14904642 | 0.80 | NPC1 (0.39) | NPC1RAB9AALDH1A1DGAT1NAMPT | |
| SCHEMBL2689967 | 0.80 | ALDH1A1 (0.36) | NPC1RAB9AALDH1A1DGAT1MAPK1 | |
| SCHEMBL14904691 | 0.80 | NPC1 (0.36) | NPC1RAB9AALDH1A1DGAT1NAMPT | |
| SCHEMBL14904668 | 0.79 | NPC1 (0.37) | NPC1RAB9AALDH1A1DGAT1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9591857-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES LLC (US) | 2017-03-14 | — | — | US | disclosed |