Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15356713 | 0.90 | NPC1 (0.35) | NPC1RAB9AGRM1ALDH1A1DGAT1 | |
| SCHEMBL18627132 | 0.90 | NPC1 (0.35) | NPC1RAB9AGRM1ALDH1A1DGAT1 | |
| SCHEMBL4967874 | 0.90 | ALDH1A1 (0.35) | NPC1RAB9AGRM1ALDH1A1DGAT1 | |
| SCHEMBL14904618 | 0.89 | NPC1 (0.40) | NPC1RAB9AGRM1DGAT1NAMPT | |
| SCHEMBL4969186 | 0.89 | NPC1 (0.38) | NPC1RAB9AALDH1A1DGAT1NAMPT | |
| SCHEMBL4966406 | 0.86 | CACNA2D1 (0.39) | NPC1RAB9AALDH1A1DGAT1MAPK1 | |
| SCHEMBL15363490 | 0.86 | NPC1 (0.38) | NPC1RAB9AALDH1A1DGAT1LMNA | |
| SCHEMBL15363445 | 0.83 | SLC6A9 (0.33) | — | |
| SCHEMBL4971802 | 0.83 | DGAT1 (0.39) | NPC1RAB9AGRM1ALDH1A1DGAT1 | |
| SCHEMBL14904688 | 0.83 | NPC1 (0.39) | NPC1RAB9AALDH1A1DGAT1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10165775-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES LLC (US) | 2019-01-01 | — | — | US | disclosed |
| US-9708288-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES LLC (US) | 2017-07-18 | — | — | US | disclosed |
| US-9708288-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES LLC (US) | 2017-07-18 | — | — | US | disclosed |
| US-9655365-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES LLC (US) | 2017-05-23 | — | — | US | disclosed |
| US-9655365-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES LLC (US) | 2017-05-23 | — | — | US | disclosed |
| US-20160318924-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2016-11-03 | — | — | US | disclosed |
| US-9422278-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES LLC (US) | 2016-08-23 | — | — | US | disclosed |
| US-9422278-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES LLC (US) | 2016-08-23 | — | — | US | disclosed |
| US-9282739-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES LLC (US) | 2016-03-15 | — | — | US | disclosed |
| US-20150166531-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2015-06-18 | — | — | US | disclosed |
| US-8901153-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES, LLC. (US) | 2014-12-02 | — | — | US | disclosed |
| US-8901153-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES, LLC. (US) | 2014-12-02 | — | — | US | disclosed |
| US-8815271-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES, LLC. (US) | 2014-08-26 | — | — | US | disclosed |
| US-8815271-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES, LLC. (US) | 2014-08-26 | — | — | US | disclosed |
| US-20140213448-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2014-07-31 | — | — | US | disclosed |
| US-20130291227-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2013-10-31 | — | — | US | disclosed |
| WO-2012061290-A2 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2012-05-10 | — | — | WO | disclosed |
| US-20120110702-A1 | Pesticidal Compositions and Processes Related Thereto | CORTEVA AGRISCIENCE LLC | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160318924-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | ACHE, DDT, PTMS | NPC1 3920/4885RAB9A 980/4885GRM1 2514/4885 |
| US-20130291227-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | ACHE, DDT, PTMS | NPC1 3920/4885RAB9A 980/4885GRM1 2514/4885 |
| US-20140213448-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | ACHE, DDT, PTMS | NPC1 3920/4885RAB9A 980/4885GRM1 2514/4885 |
| US-20150166531-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | ACHE, DDT, PTMS | NPC1 3920/4885RAB9A 980/4885GRM1 2514/4885 |
| US-10165775-B2 | Pesticidal compositions and processes related thereto | ACHE, DDT, PTMS | NPC1 3920/4885RAB9A 980/4885GRM1 2514/4885 |
| US-20120110702-A1 | Pesticidal Compositions and Processes Related Thereto | ACHE, DDT, PTMS | NPC1 3920/4885RAB9A 980/4885GRM1 2514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.