SCHEMBL18622800

SCHEMBL18622800

c1ccc(-n2c3ccccc3c3ccc(-n4c5ccccc5c5ccc(-c6ccc7c(c6)Oc6cc8ccccc8cc6O7)cc54)cc32)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 3/20 0.45
▸ KDM4E B2RXH2 1/20 0.45
▸ ATM Q13315 1/20 0.45
▸ EDNRA P25101 5/20 0.39
▸ EDNRB P24530 1/20 0.39
▸ NPC1 O15118 1/20 0.34
▸ RAB9A P51151 1/20 0.34
▸ HDAC4 P56524 1/20 0.34
▸ F2 P00734 1/20 0.32
▸ F10 P00742 1/20 0.32
▸ PRSS1 P07477 1/20 0.32
▸ MAT2A P31153 1/20 0.32
▸ PTPN1 P18031 1/20 0.32
▸ MAPK8 P45983 2/20 0.32
▸ KMT2A Q03164 2/20 0.32
▸ IL1R1 P14778 1/20 0.32
▸ ALDH1A1 P00352 2/20 0.31
▸ TSHR P16473 1/20 0.31
▸ RXRA P19793 1/20 0.31
▸ RXRB P28702 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18622792 0.96 L3MBTL1 (0.49) L3MBTL1KDM4EATMEDNRAEDNRB
SCHEMBL18622788 0.95 L3MBTL1 (0.43) L3MBTL1KDM4EATMEDNRAEDNRB
SCHEMBL18622766 0.89 L3MBTL1 (0.46) L3MBTL1KDM4EATMEDNRAEDNRB
SCHEMBL18622804 0.88 KDM4E (0.38) L3MBTL1KDM4EATMEDNRAEDNRB
SCHEMBL18622803 0.87 L3MBTL1 (0.47) L3MBTL1KDM4EATMEDNRAEDNRB
SCHEMBL18622801 0.86 L3MBTL1 (0.36) L3MBTL1KDM4EATMEDNRAEDNRB
SCHEMBL18622814 0.86 EDNRA (0.44) L3MBTL1KDM4EATMEDNRAEDNRB
SCHEMBL18622780 0.85 EDNRA (0.39) L3MBTL1KDM4EATMEDNRAEDNRB
SCHEMBL18622774 0.85 L3MBTL1 (0.45) L3MBTL1KDM4EATMEDNRAEDNRB
SCHEMBL18622815 0.84 KDM4E (0.41) L3MBTL1KDM4EATMEDNRAEDNRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10249830-B2 Carbazole-based compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2019-04-02 — — US disclosed
US-20170077419-A1 CARBAZOLE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-03-16 — — US disclosed
US-20170077419-A1 CARBAZOLE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-03-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10249830-B2 Carbazole-based compound and organic light-emitting device including the same OCIAD1, OXA1L, OCIAD2 L3MBTL1 50/4885KDM4E 3223/4885ATM 3873/4885
US-20170077419-A1 CARBAZOLE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME OCIAD1, OXA1L, CYP1A1 L3MBTL1 34/4885KDM4E 3224/4885ATM 3712/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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