SCHEMBL18622814

SCHEMBL18622814

c1ccc2cc3c(cc2c1)Oc1ccc(-c2ccc4c(c2)c2ccccc2n4-c2ccc4c(c2)Oc2cc5ccccc5cc2O4)cc1O3

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ EDNRA P25101 5/20 0.44
▸ EDNRB P24530 4/20 0.44
▸ L3MBTL1 Q9Y468 4/20 0.38
▸ KDM4E B2RXH2 2/20 0.38
▸ ATM Q13315 1/20 0.38
▸ ALOX5 P09917 1/20 0.33
▸ NPY5R Q15761 2/20 0.33
▸ TDP1 Q9NUW8 1/20 0.33
▸ RAC2 P15153 1/20 0.32
▸ RAC3 P60763 1/20 0.32
▸ CDC42 P60953 1/20 0.32
▸ RAC1 P63000 1/20 0.32
▸ PTGER4 P35408 2/20 0.32
▸ NPC1 O15118 2/20 0.32
▸ RAB9A P51151 2/20 0.32
▸ TSPO P30536 2/20 0.31
▸ HDAC4 P56524 1/20 0.31
▸ MEN1 O00255 1/20 0.31
▸ ALDH1A1 P00352 1/20 0.31
▸ MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18622780 0.94 EDNRA (0.39) EDNRAEDNRBL3MBTL1KDM4EATM
SCHEMBL18622803 0.91 L3MBTL1 (0.47) EDNRAEDNRBL3MBTL1KDM4EATM
SCHEMBL18622788 0.89 L3MBTL1 (0.43) EDNRAEDNRBL3MBTL1KDM4EATM
SCHEMBL18622774 0.88 L3MBTL1 (0.45) EDNRAEDNRBL3MBTL1KDM4EATM
SCHEMBL18622815 0.87 KDM4E (0.41) EDNRAEDNRBL3MBTL1KDM4EATM
SCHEMBL18622767 0.86 L3MBTL1 (0.49) EDNRAEDNRBL3MBTL1KDM4EATM
SCHEMBL18622790 0.86 KDM4E (0.38) EDNRAEDNRBL3MBTL1KDM4EATM
SCHEMBL18622800 0.86 L3MBTL1 (0.45) EDNRAEDNRBL3MBTL1KDM4EATM
SCHEMBL18622807 0.86 L3MBTL1 (0.45) EDNRAEDNRBL3MBTL1KDM4EATM
SCHEMBL18622764 0.85 L3MBTL1 (0.46) EDNRAEDNRBL3MBTL1KDM4EATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10249830-B2 Carbazole-based compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2019-04-02 — — US disclosed
US-20170077419-A1 CARBAZOLE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-03-16 — — US disclosed
US-20170077419-A1 CARBAZOLE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-03-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10249830-B2 Carbazole-based compound and organic light-emitting device including the same OCIAD1, OXA1L, OCIAD2 EDNRA 4411/4885EDNRB 4434/4885L3MBTL1 50/4885
US-20170077419-A1 CARBAZOLE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME OCIAD1, OXA1L, CYP1A1 EDNRA 4309/4885EDNRB 4454/4885L3MBTL1 34/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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