Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17008991 | 0.84 | RXFP1 (0.52) | MAPK1ALOX15HSD17B10ALDH1A1HPGD | |
| SCHEMBL9952117 | 0.77 | MAPK1 (0.54) | MAPK1ALOX15HSD17B10ALDH1A1HPGD | |
| SCHEMBL9952069 | 0.75 | HSD17B10 (0.50) | MAPK1ALOX15HSD17B10ALDH1A1HPGD | |
| SCHEMBL17286442 | 0.74 | MAPK1 (0.62) | MAPK1ALOX15HSD17B10ALDH1A1HPGD | |
| SCHEMBL16666910 | 0.74 | RXFP1 (0.51) | MAPK1ALOX15HSD17B10ALDH1A1HPGD | |
| SCHEMBL15427212 | 0.74 | HSD17B10 (0.51) | MAPK1ALOX15HSD17B10ALDH1A1HPGD | |
| SCHEMBL9952680 | 0.72 | RXFP1 (0.49) | MAPK1ALOX15HSD17B10ALDH1A1HPGD | |
| SCHEMBL9952288 | 0.71 | RXFP1 (0.48) | MAPK1ALOX15HSD17B10ALDH1A1HPGD | |
| SCHEMBL6942406 | 0.70 | HPGD (0.57) | MAPK1ALOX15HSD17B10ALDH1A1HPGD | |
| SCHEMBL10839920 | 0.70 | HPGD (0.61) | MAPK1ALOX15HSD17B10ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170073342-A1 | 2-(HET)ARYL-SUBSTITUTED FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170073342-A1 | 2-(HET)ARYL-SUBSTITUTED FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | CYP1B1, CYP4B1, CYP8B1 | MAPK1 2792/4885ALOX15 185/4885HSD17B10 149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.