Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CTSD | P07339 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6939482 | 0.86 | KMT2A (0.50) | HPGDHSD17B10ALOX15ALDH1A1L3MBTL1 | |
| SCHEMBL10839920 | 0.86 | HPGD (0.61) | HPGDHSD17B10ALOX15ALDH1A1MAPK1 | |
| SCHEMBL8623561 | 0.84 | L3MBTL1 (0.72) | HPGDHSD17B10ALOX15ALDH1A1MAPK1 | |
| SCHEMBL6564706 | 0.83 | PTGS2 (0.54) | HPGDHSD17B10ALOX15ALDH1A1L3MBTL1 | |
| SCHEMBL2747139 | 0.81 | HSD17B10 (0.49) | HPGDHSD17B10ALOX15ALDH1A1MAPK1 | |
| SCHEMBL3356549 | 0.81 | SIRT1 (0.55) | HPGDHSD17B10ALOX15ALDH1A1MAPK1 | |
| SCHEMBL6939026 | 0.81 | KMT2A (0.63) | HPGDHSD17B10ALDH1A1L3MBTL1TDP1 | |
| SCHEMBL8552689 | 0.81 | HPGD (0.53) | HPGDHSD17B10ALOX15ALDH1A1MAPK1 | |
| SCHEMBL6940650 | 0.81 | CTSD (0.46) | HPGDHSD17B10ALOX15ALDH1A1L3MBTL1 | |
| SCHEMBL6935895 | 0.81 | CTSD (0.46) | HPGDHSD17B10ALOX15ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272456-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | Abbott Laboratories (US) | 2003-01-08 | — | — | EP | claimed |
| WO-2001079157-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | ABBOTT LABORATORIES (US) | 2001-10-25 | — | — | WO | claimed |