Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 3/20 | 0.44 |
| ▸ | RXRB | P28702 | 3/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | BAD | Q92934 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | RARA | P10276 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 1/20 | 0.43 |
| ▸ | RARG | P13631 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25126172 | 0.82 | RXRA (0.59) | FOLH1TP53TSHRRXRARXRB | |
| SCHEMBL7919905 | 0.81 | DPP4 (0.66) | FOLH1LOXL2TP53TSHRRXRA | |
| SCHEMBL23877798 | 0.81 | FOLH1 (0.48) | FOLH1LOXL2RXRARXRBSRD5A2 | |
| SCHEMBL23658408 | 0.81 | HSD17B10 (0.49) | FOLH1LOXL2SRD5A2CA12CA1 | |
| SCHEMBL18624970 | 0.80 | TTR (0.46) | LOXL2TP53TSHRSRD5A2CA12 | |
| SCHEMBL28374522 | 0.78 | RARB (0.53) | FOLH1TP53RXRARXRBRARA | |
| SCHEMBL29199190 | 0.77 | TSHR (0.63) | TP53TSHRRXRARXRBBCL2L1 | |
| SCHEMBL23501870 | 0.77 | TSHR (0.63) | FOLH1TP53TSHRRXRARXRB | |
| SCHEMBL2942251 | 0.77 | TSHR (0.63) | FOLH1TP53TSHRRXRARXRB | |
| SCHEMBL22861483 | 0.77 | EGFR (0.50) | FOLH1RXRARXRBMAP4K4SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170072070-A1 | METAL-ORGANIC FRAMEWORK STIMULUS RESPONSIVE POLYMER COMPOSITE CAPABLE OF CONTROLLING RELEASE OF GUEST | NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) | 2017-03-16 | — | — | US | disclosed |
| US-20170072070-A1 | METAL-ORGANIC FRAMEWORK STIMULUS RESPONSIVE POLYMER COMPOSITE CAPABLE OF CONTROLLING RELEASE OF GUEST | NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) | 2017-03-16 | — | — | US | disclosed |
| EP-3141263-A1 | METAL-ORGANIC FRAMEWORK/STIMULUS-RESPONSIVE POLYMER COMPOSITE CAPABLE OF CONTROLLING RELEASE OF GUEST | National University Corporation Hokkaido University (JP) | 2017-03-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170072070-A1 | METAL-ORGANIC FRAMEWORK STIMULUS RESPONSIVE POLYMER COMPOSITE CAPABLE OF CONTROLLING RELEASE OF GUEST | ORAI1, SARAF, TRPM8 | FOLH1 2971/4885LOXL2 2713/4885TP53 3141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.