Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.58 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | SCD | O00767 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SCN1A | P35498 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 3/20 | 0.36 |
| ▸ | FNTB | P49356 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1393863 | 0.81 | CA12 (0.55) | CA12CA1CA2CA9CA14 | |
| SCHEMBL1393864 | 0.81 | CA12 (0.55) | CA12CA1CA2CA9CA14 | |
| SCHEMBL28648102 | 0.80 | LMNA (0.50) | ALDH1A1LMNASCN1ASCN2ASCN3A | |
| SCHEMBL24209235 | 0.80 | SCN1A (0.59) | CA12CA1CA2CA9CA14 | |
| SCHEMBL14297345 | 0.79 | CA12 (0.65) | CA12CA1CA2CA9CA14 | |
| SCHEMBL18364959 | 0.79 | CA12 (0.65) | CA12CA1CA2CA9CA14 | |
| SCHEMBL6646101 | 0.77 | CA1 (0.63) | CA12CA1CA2CA9CA14 | |
| SCHEMBL28856783 | 0.77 | CA2 (0.68) | CA12CA1CA2CA9CA14 | |
| SCHEMBL7210123 | 0.77 | CA12 (0.68) | CA12CA1CA2CA9CA14 | |
| SCHEMBL2601677 | 0.77 | CA12 (0.63) | CA12CA1CA2CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9593080-B1 | Triazabutadienes as cleavable cross-linkers | THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2017-03-14 | — | — | US | disclosed |