Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.50 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.50 |
| ▸ | FKBP1A | P62942 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.45 |
| ▸ | PREP | P48147 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24705627 | 1.00 | SPHK1 (0.50) | SPHK1MMEL1FKBP1AALDH1A1SMN1; SMN2 | |
| SCHEMBL20966402 | 0.90 | SPHK1 (0.58) | SPHK1MMEL1FKBP1AALDH1A1SMN1; SMN2 | |
| SCHEMBL14836855 | 0.90 | MMEL1 (0.52) | SPHK1MMEL1FKBP1AALDH1A1SMN1; SMN2 | |
| SCHEMBL19880370 | 0.86 | SMN1; SMN2 (0.51) | MMEL1FKBP1AALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL19880369 | 0.86 | SMN1; SMN2 (0.51) | MMEL1FKBP1AALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL18734805 | 0.86 | SMN1; SMN2 (0.51) | MMEL1FKBP1AALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL2707345 | 0.85 | MMEL1 (0.58) | MMEL1FKBP1AALDH1A1CTRB1PREP | |
| SCHEMBL20966406 | 0.85 | MMEL1 (0.53) | SPHK1MMEL1FKBP1ASMN1; SMN2CYP2C19 | |
| SCHEMBL934366 | 0.85 | MMEL1 (0.58) | MMEL1FKBP1AALDH1A1CTRB1PREP | |
| SCHEMBL20993944 | 0.84 | MMEL1 (0.65) | MMEL1FKBP1AALDH1A1SMN1; SMN2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210332061-A1 | NMDA RECEPTOR MODULATORS AND USES THEREOF | NAUREX, INC. | 2021-10-28 | — | — | US | disclosed |
| US-10906913-B2 | NMDA receptor modulators and uses thereof | NORTHWESTERN UNIVERSITY (US) | 2021-02-02 | — | — | US | disclosed |
| US-20190077807-A1 | NMDA RECEPTOR MODULATORS AND USES THEREOF | NAUREX, INC. | 2019-03-14 | — | — | US | disclosed |
| US-9802946-B2 | NMDA receptor modulators and uses thereof | NORTHWESTERN UNIVERSITY (US) | 2017-10-31 | — | — | US | disclosed |
| US-9593145-B2 | Secondary structure stabilized NMDA receptor modulators and uses thereof | NORTHWESTERN UNIVERSITY (US) | 2017-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190077807-A1 | NMDA RECEPTOR MODULATORS AND USES THEREOF | GRIN1, GRIN2A, GRIN3A | SPHK1 3133/4885MMEL1 710/4885FKBP1A 3138/4885 |
| US-20210332061-A1 | NMDA RECEPTOR MODULATORS AND USES THEREOF | GRIN1, GRIN2A, GRIN3A | SPHK1 3133/4885MMEL1 710/4885FKBP1A 3138/4885 |
| US-10906913-B2 | NMDA receptor modulators and uses thereof | GRIN1, GRIN2A, GRIN3A | SPHK1 3133/4885MMEL1 710/4885FKBP1A 3138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.