SCHEMBL18626366

SCHEMBL18626366

C=C/C=c1\c(=C/C)n(C)c2ccccc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GPR3 P46089 1/20 0.44
▸ KDM4E B2RXH2 7/20 0.38
▸ MAPT P10636 2/20 0.38
▸ ALKBH5 Q6P6C2 1/20 0.35
▸ FTO Q9C0B1 1/20 0.35
▸ ALDH1A1 P00352 4/20 0.34
▸ NQO2 P16083 2/20 0.34
▸ LMNA P02545 2/20 0.34
▸ HTR2A P28223 1/20 0.34
▸ HTR2C P28335 1/20 0.34
▸ TSHR P16473 2/20 0.34
▸ HSD17B10 Q99714 3/20 0.33
▸ ERCC1 P07992 1/20 0.33
▸ FEN1 P39748 1/20 0.33
▸ ERCC4 Q92889 1/20 0.33
▸ LIMK1 P53667 1/20 0.33
▸ ALOX15 P16050 1/20 0.33
▸ MAPK1 P28482 1/20 0.33
▸ GABRP O00591 1/20 0.33
▸ GABRD O14764 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18713340 0.90 GPR3 (0.47) GPR3KDM4EMAPTALKBH5FTO
SCHEMBL23874998 0.88 GPR3 (0.45) GPR3KDM4EMAPTALKBH5FTO
SCHEMBL18746036 0.88 GPR3 (0.52) GPR3KDM4EMAPTALKBH5FTO
SCHEMBL16870944 0.82 GPR3 (0.31) GPR3
SCHEMBL21578607 0.82 GPR3 (0.31) GPR3
SCHEMBL19774619 0.82 GPR3 (0.31) GPR3
SCHEMBL24667834 0.81 MAPT (0.39) KDM4EMAPTALDH1A1LMNATSHR
SCHEMBL24667906 0.80 — —
SCHEMBL20751954 0.80 KDM4E (0.46) KDM4EMAPTALDH1A1LMNAHSD17B10
SCHEMBL23625525 0.79 GPR3 (0.47) GPR3KDM4EMAPTALKBH5FTO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4307402-A1 ORGANIC LIGHT EMITTING DEVICE Lg Chem, Ltd. (KR) 2024-01-17 — — EP disclosed
US-20230399350-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-12-14 — — US disclosed
US-11706981-B2 Organic light emitting device and compounds for use in same IDEMITSU KOSAN CO., LTD. (JP) 2023-07-18 — — US disclosed
US-20230210001-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 — — US disclosed
US-20230200231-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-22 — — US disclosed
WO-2021135725-A1 ORGANIC COMPOUND, ELECTRONIC DEVICE AND ELECTRONIC APPARATUS USING SAME 陕西莱特光电材料股份有限公司 2021-07-08 — — WO disclosed
US-20200227652-A1 ORGANIC LIGHT EMITTING DEVICE AND COMPOUNDS FOR USE IN SAME IDEMITSU KOSAN CO., LTD. (JP) 2020-07-16 — — US disclosed
US-10700284-B2 Photoactive composition LG CHEM, LTD. (KR) 2020-06-30 — — US disclosed
US-9595680-B2 Heterocyclic fluorescent dyes and method of production thereof BASF SE (DE) 2017-03-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230399350-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP GPR3 1497/4885KDM4E 3953/4885MAPT 194/4885
US-11706981-B2 Organic light emitting device and compounds for use in same SLCO4C1, XPO6, ERCC1 GPR3 1925/4885KDM4E 4493/4885MAPT 485/4885
US-10700284-B2 Photoactive composition L1CAM, EPCAM, GJB2 GPR3 4133/4885KDM4E 4117/4885MAPT 1012/4885
US-20200227652-A1 ORGANIC LIGHT EMITTING DEVICE AND COMPOUNDS FOR USE IN SAME SLCO4C1, XPO6, ERCC1 GPR3 1925/4885KDM4E 4493/4885MAPT 485/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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