Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
| ▸ | ACP1 | P24666 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10258235 | 0.81 | CETP (0.44) | GPR119USP30CETPKDM4E | |
| SCHEMBL16941148 | 0.80 | GPR119 (0.43) | GPR119JAK2JAK1USP30PTPN2 | |
| SCHEMBL1909822 | 0.76 | USP30 (0.43) | GPR119USP30PTPN2PTPN1PTPN6 | |
| SCHEMBL18279997 | 0.75 | KDM4E (0.59) | GPR119USP30PTPN2PTPN1PTPN6 | |
| SCHEMBL19605627 | 0.71 | KLK7 (0.45) | USP30STSCETP | |
| SCHEMBL20374862 | 0.71 | NR1H2 (0.46) | USP30 | |
| SCHEMBL18724921 | 0.71 | KLK7 (0.45) | USP30STSCETP | |
| SCHEMBL19605628 | 0.71 | KLK7 (0.45) | USP30STSCETP | |
| SCHEMBL9963887 | 0.71 | KLK7 (0.45) | USP30STSCETP | |
| SCHEMBL18800923 | 0.70 | CETP (0.40) | GPR119USP30CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9593110-B2 | Neprilysin inhibitors | Theravence Biopharma R&D IP, LLC (US) | 2017-03-14 | — | — | US | disclosed |