Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 5/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.38 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10252545 | 0.86 | SMN1; SMN2 (0.38) | ABCB1ABHD6DAGLACYP3A4KDM4E | |
| SCHEMBL10257175 | 0.85 | HTR2C (0.50) | KMT2A | |
| SCHEMBL1909822 | 0.82 | USP30 (0.43) | CETPUSP30NR1H2NR1H3ABCB1 | |
| SCHEMBL18626470 | 0.81 | GPR119 (0.43) | CETPUSP30GPR119KDM4E | |
| SCHEMBL1908567 | 0.79 | KLK7 (0.45) | CETPUSP30NR1H2NR1H3DPP4 | |
| SCHEMBL9963887 | 0.79 | KLK7 (0.45) | CETPUSP30NR1H2NR1H3DPP4 | |
| SCHEMBL19605627 | 0.79 | KLK7 (0.45) | CETPUSP30NR1H2NR1H3DPP4 | |
| SCHEMBL20374862 | 0.79 | NR1H2 (0.46) | USP30NR1H2NR1H3ABCB1DPP4 | |
| SCHEMBL598389 | 0.79 | KLK7 (0.45) | CETPUSP30NR1H2NR1H3DPP4 | |
| SCHEMBL19605628 | 0.79 | KLK7 (0.45) | CETPUSP30NR1H2NR1H3DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142916-A1 | PROCESS FOR PREPARING 5-BIPHENYL-4-AMINO-2-METHYL PENTANOIC ACID | NOVARTIS AG (CH) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142916-A1 | PROCESS FOR PREPARING 5-BIPHENYL-4-AMINO-2-METHYL PENTANOIC ACID | MME, REN, PAH | CETP 2802/4885USP30 793/4885NR1H2 4029/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.