Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1231703 | 1.00 | CA12 (0.39) | CA12CA1CA2CA9GPR119 | |
| SCHEMBL2378473 | 0.90 | CA12 (0.45) | CA12CA1CA2CA9GPR119 | |
| SCHEMBL6646583 | 0.90 | CA12 (0.48) | CA12CA1CA2CA9GPR119 | |
| SCHEMBL14937974 | 0.87 | CA12 (0.47) | CA12CA1CA2CA9TSHR | |
| SCHEMBL3377039 | 0.87 | CA12 (0.47) | CA12CA1CA2CA9TSHR | |
| SCHEMBL3381746 | 0.83 | TSHR (0.42) | GPR119TSHR | |
| SCHEMBL27881190 | 0.83 | CA12 (0.52) | CA12CA1CA2CA9TSHR | |
| SCHEMBL2372804 | 0.83 | CA12 (0.52) | CA12CA1CA2CA9TSHR | |
| SCHEMBL5754253 | 0.79 | CA12 (0.34) | CA12CA1CA2CA9GPR119 | |
| SCHEMBL15917112 | 0.78 | CA12 (0.33) | CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323651-A2 | COMPOUNDS FOR THE TREATMENT OF FLAVIVIRAL INFECTIONS | Summit Corporation Plc (GB) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010049678-A2 | TREATMENT OF ENERGY UTILIZATION DISEASES | SUMMIT CORPORATION PLC (GB) | 2010-05-06 | — | — | WO | disclosed |
| WO-2010029313-A1 | ANTIINFECTIVE COMPOUNDS | SUMMIT CORPORATION PLC. (GB) | 2010-03-18 | — | — | WO | disclosed |
| WO-2010015815-A2 | COMPOUNDS FOR THE TREATMENT OF FLAVIVIRAL INFECTIONS | SUMMIT CORPORATION PLC (GB) | 2010-02-11 | — | — | WO | disclosed |