Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAN2B1 | O00754 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2378473 | 0.95 | CA12 (0.45) | CA12CA1CA2CA9TSHR | |
| SCHEMBL2372804 | 0.95 | CA12 (0.52) | CA12CA1CA2CA9TSHR | |
| SCHEMBL27881190 | 0.95 | CA12 (0.52) | CA12CA1CA2CA9TSHR | |
| SCHEMBL1231703 | 0.90 | CA12 (0.39) | CA12CA1CA2CA9TSHR | |
| SCHEMBL1862926 | 0.90 | CA12 (0.39) | CA12CA1CA2CA9TSHR | |
| SCHEMBL3377039 | 0.87 | CA12 (0.47) | CA12CA1CA2CA9TSHR | |
| SCHEMBL14937974 | 0.87 | CA12 (0.47) | CA12CA1CA2CA9TSHR | |
| SCHEMBL5754253 | 0.79 | CA12 (0.34) | CA12CA1CA2CA9GPR119 | |
| SCHEMBL27518151 | 0.78 | CA12 (0.37) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL15917112 | 0.73 | CA12 (0.33) | CA12CA1CA2CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1456175-A1 | SUBSTITUTED HETEROCYCLIC CARBOXAMIDES WITH ANTITHROMBOTIC ACTIVITY | ELI LILLY AND COMPANY (US) | 2004-09-15 | — | — | EP | disclosed |
| WO-2003050088-A1 | SUBSTITUTED HETEROCYCLIC CARBOXAMIDES WITH ANTITHROMBOTIC ACTIVITY | ELI LILLY AND COMPANY (US) | 2003-06-19 | — | — | WO | disclosed |