Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R46 | P59540 | 8/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.32 |
| ▸ | TAS2R31 | P59538 | 2/20 | 0.32 |
| ▸ | TAS2R10 | Q9NYW0 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9240553 | 1.00 | TAS2R46 (0.47) | TAS2R46MEN1KMT2ACYP1A2ALDH1A1 | |
| SCHEMBL8635163 | 1.00 | TAS2R46 (0.47) | TAS2R46MEN1KMT2ACYP1A2ALDH1A1 | |
| SCHEMBL8628231 | 1.00 | TAS2R46 (0.47) | TAS2R46MEN1KMT2ACYP1A2ALDH1A1 | |
| SCHEMBL754420 | 1.00 | TAS2R46 (0.47) | TAS2R46MEN1KMT2ACYP1A2ALDH1A1 | |
| SCHEMBL4097512 | 1.00 | TAS2R46 (0.47) | TAS2R46MEN1KMT2ACYP1A2ALDH1A1 | |
| SCHEMBL9244208 | 1.00 | TAS2R46 (0.47) | TAS2R46MEN1KMT2ACYP1A2ALDH1A1 | |
| SCHEMBL24026904 | 1.00 | TAS2R46 (0.47) | TAS2R46MEN1KMT2ACYP1A2ALDH1A1 | |
| SCHEMBL13478756 | 1.00 | TAS2R46 (0.47) | TAS2R46MEN1KMT2ACYP1A2ALDH1A1 | |
| SCHEMBL21316644 | 1.00 | TAS2R46 (0.47) | TAS2R46MEN1KMT2ACYP1A2ALDH1A1 | |
| SCHEMBL8632758 | 1.00 | TAS2R46 (0.47) | TAS2R46MEN1KMT2ACYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3347348-B1 | PREPARATION OF 3-HYDROXY-3,6-DIMETHYLHEXAHYDROBENZOFURAN-2-ONE AND DERIVATIVES THEREOF | P2 SCIENCE INC (US) | 2021-11-17 | — | — | EP | disclosed |
| WO-2017044957-A1 | PREPARATION OF 3-HYDROXY-3,6-DIMETHYLHEXAHYDROBENZOFURAN-2-ONE AND DERIVATIVES THEREOF | P2 SCIENCE, INC. (US) | 2017-03-16 | — | — | WO | disclosed |