Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAE1 | Q13564 | 3/20 | 0.63 |
| ▸ | UBA3 | Q8TBC4 | 2/20 | 0.63 |
| ▸ | UBA6 | A0AVT1 | 1/20 | 0.63 |
| ▸ | ATG7 | O95352 | 1/20 | 0.63 |
| ▸ | UBA7 | P41226 | 1/20 | 0.63 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18630470 | 1.00 | NAE1 (0.63) | NAE1UBA3UBA6ATG7UBA7 | |
| SCHEMBL18630548 | 0.87 | NAE1 (0.67) | NAE1UBA3UBA6ATG7UBA7 | |
| SCHEMBL18630397 | 0.87 | NAE1 (0.67) | NAE1UBA3UBA6ATG7UBA7 | |
| SCHEMBL18631624 | 0.84 | NAE1 (0.56) | NAE1UBA3UBA6ATG7UBA7 | |
| SCHEMBL18631612 | 0.81 | NAE1 (0.63) | NAE1UBA3UBA6ATG7UBA7 | |
| SCHEMBL18630408 | 0.81 | NAE1 (0.62) | NAE1UBA3UBA6ATG7UBA7 | |
| SCHEMBL18630428 | 0.81 | NAE1 (0.62) | NAE1UBA3UBA6ATG7UBA7 | |
| SCHEMBL18630406 | 0.80 | NAE1 (0.66) | NAE1UBA3UBA6ATG7UBA7 | |
| SCHEMBL18630522 | 0.79 | ADORA3 (0.56) | — | |
| SCHEMBL1800297 | 0.79 | UBA6 (0.80) | NAE1UBA3UBA6ATG7UBA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170073367-A9 | SUBSTITUTED PYRROLO[2,3-D]PYRIMIDINES | MILLENIUM PHARMACEUTICALS, INC. | 2017-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170073367-A9 | SUBSTITUTED PYRROLO[2,3-D]PYRIMIDINES | TYMP, TYMS, PPA1 | NAE1 257/4885UBA3 235/4885UBA6 2037/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.