Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | FPR1 | P21462 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1700192 | 1.00 | ALDH1A1 (0.35) | ALDH1A1PKMHRH3SIGMAR1HTR4 | |
| SCHEMBL1867290 | 1.00 | ALDH1A1 (0.35) | ALDH1A1PKMHRH3SIGMAR1HTR4 | |
| SCHEMBL1865474 | 0.88 | CCR8 (0.32) | SIGMAR1KDM2B | |
| SCHEMBL1700425 | 0.88 | CCR8 (0.32) | SIGMAR1KDM2B | |
| SCHEMBL5312840 | 0.75 | TACR2 (0.38) | HTR4 | |
| SCHEMBL1700055 | 0.73 | EPHX2 (0.36) | — | |
| SCHEMBL1700046 | 0.71 | TSHR (0.43) | ALDH1A1 | |
| SCHEMBL1958107 | 0.70 | — | — | |
| SCHEMBL20756541 | 0.70 | HRH3 (0.35) | ALDH1A1PKMHRH3MCHR1KDM4E | |
| SCHEMBL12458632 | 0.70 | HRH3 (0.35) | ALDH1A1PKMHRH3MCHR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010138588-A9 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | ABBOTT LABORATORIES (US) | 2011-05-05 | — | — | WO | disclosed |