Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR8 | P51685 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1700425 | 1.00 | CCR8 (0.32) | CCR8SIGMAR1KDM2B | |
| SCHEMBL1863283 | 0.88 | ALDH1A1 (0.35) | SIGMAR1KDM2B | |
| SCHEMBL1867290 | 0.88 | ALDH1A1 (0.35) | SIGMAR1KDM2B | |
| SCHEMBL1700192 | 0.88 | ALDH1A1 (0.35) | SIGMAR1KDM2B | |
| SCHEMBL1958107 | 0.79 | — | — | |
| SCHEMBL1700055 | 0.74 | EPHX2 (0.36) | — | |
| SCHEMBL1700046 | 0.72 | TSHR (0.43) | — | |
| SCHEMBL2276120 | 0.70 | TP53 (0.34) | — | |
| SCHEMBL1700073 | 0.69 | EPHX2 (0.35) | SIGMAR1 | |
| SCHEMBL23337914 | 0.69 | MAP3K12 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010138588-A9 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | ABBOTT LABORATORIES (US) | 2011-05-05 | — | — | WO | disclosed |