Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB4 | Q15303 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18633103 | 0.85 | EGFR (0.42) | EGFR | |
| SCHEMBL18633146 | 0.81 | EGFR (0.46) | EGFR | |
| SCHEMBL18633114 | 0.77 | CA1 (0.33) | — | |
| SCHEMBL18633116 | 0.76 | ERBB4 (0.57) | ERBB4EGFR | |
| SCHEMBL15090640 | 0.71 | EGFR (0.56) | EGFR | |
| SCHEMBL15090803 | 0.66 | EGFR (0.61) | EGFR | |
| SCHEMBL18633151 | 0.64 | EGFR (0.58) | EGFR | |
| SCHEMBL18632975 | 0.64 | EGFR (0.52) | ERBB4EGFR | |
| SCHEMBL18633111 | 0.60 | EGFR (0.57) | EGFR | |
| SCHEMBL15090653 | 0.60 | EGFR (0.71) | ERBB4EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2612860-B1 | QUINAZOLINE DERIVATIVES SUBSTITUTED BY ANILINE, PREPARATION METHOD AND USE THEREOF | XUANZHU PHARMA CO LTD (CN) | 2017-03-15 | — | — | EP | disclosed |