Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 18/20 | 0.46 |
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15090640 | 0.90 | EGFR (0.56) | EGFREPHA2KDREPHB4 | |
| SCHEMBL15090803 | 0.86 | EGFR (0.61) | EGFRFBP1EPHA2KDREPHB4 | |
| SCHEMBL18633151 | 0.83 | EGFR (0.58) | EGFRFBP1KDR | |
| SCHEMBL18633112 | 0.81 | ERBB4 (0.32) | EGFR | |
| SCHEMBL18862789 | 0.79 | EGFR (0.63) | EGFRFBP1KDREPHB4 | |
| SCHEMBL15090653 | 0.79 | EGFR (0.71) | EGFR | |
| SCHEMBL18633111 | 0.78 | EGFR (0.57) | EGFRFBP1 | |
| SCHEMBL15106854 | 0.78 | EGFR (0.58) | EGFRFBP1EPHA2KDREPHB4 | |
| SCHEMBL15090622 | 0.77 | EGFR (0.70) | EGFRFBP1EPHA2KDREPHB4 | |
| SCHEMBL14388259 | 0.76 | EIF2AK2 (0.44) | EGFRFBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2612860-B1 | QUINAZOLINE DERIVATIVES SUBSTITUTED BY ANILINE, PREPARATION METHOD AND USE THEREOF | XUANZHU PHARMA CO LTD (CN) | 2017-03-15 | — | — | EP | disclosed |