Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28286871 | 0.84 | GLA (0.38) | — | |
| SCHEMBL3698722 | 0.80 | ADORA1 (0.39) | — | |
| SCHEMBL3693696 | 0.76 | GLA (0.38) | — | |
| SCHEMBL3701880 | 0.74 | GLA (0.39) | — | |
| SCHEMBL28285520 | 0.72 | ADORA1 (0.39) | TSHR | |
| SCHEMBL30296175 | 0.72 | GLA (0.34) | — | |
| SCHEMBL3708772 | 0.69 | ALDH1A1 (0.44) | — | |
| SCHEMBL3710240 | 0.69 | PDK2 (0.36) | TSHR | |
| SCHEMBL3697669 | 0.69 | GLA (0.38) | TSHR | |
| SCHEMBL28291675 | 0.68 | GLA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3010922-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF INFLAMMATORY DISORDERS | GALAPAGOS NV (BE) | 2017-03-15 | — | — | EP | disclosed |