SCHEMBL30296175

SCHEMBL30296175

CCCc1nc(CC)c(CO)[nH]1

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.34
ADORA3 P0DMS8 1/20 0.33
ADORA2A P29274 1/20 0.33
ADORA1 P30542 1/20 0.33
POLB P06746 1/20 0.33
KDM4C Q9H3R0 1/20 0.31
SMPD3 Q9NY59 1/20 0.30
GPR84 Q9NQS5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4356818 0.90 GLA (0.35) GLAADORA3ADORA2AADORA1POLB
SCHEMBL28286871 0.86 GLA (0.38) GLAADORA3ADORA2AADORA1POLB
SCHEMBL3693696 0.86 GLA (0.38) GLAADORA3ADORA2AADORA1POLB
SCHEMBL4356446 0.79 ALDH1A1 (0.42) GPR84
SCHEMBL8982070 0.79 GLA (0.34) GLAADORA3ADORA2AADORA1POLB
SCHEMBL9081675 0.78 GPR84 (0.45) GPR84
SCHEMBL3698722 0.78 ADORA1 (0.39) GLAADORA3ADORA2AADORA1
SCHEMBL4353447 0.78 ADORA1 (0.39) ADORA3ADORA2AADORA1
SCHEMBL3697669 0.78 GLA (0.38) GLAADORA3ADORA2AADORA1POLB
SCHEMBL606 0.77 PDK2 (0.37) GLAADORA3ADORA2AADORA1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023025277-A1 AROMATIC RING-CONTAINING BIOLOGICAL ANTAGONIST, AND PREPARATION METHOD THEREFOR AND USE THEREOF 上海翰森生物医药科技有限公司 2023-03-02 WO disclosed