Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
| ▸ | FABP3 | P05413 | 3/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | PPARG | P37231 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | F7 | P08709 | 4/20 | 0.47 |
| ▸ | F3 | P13726 | 4/20 | 0.47 |
| ▸ | PPARD | Q03181 | 4/20 | 0.47 |
| ▸ | PPARA | Q07869 | 4/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | FABP4 | P15090 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18634800 | 0.89 | FAAH (0.42) | FAAHFABP3TRPV1ALDH1A1PPARG | |
| SCHEMBL28633230 | 0.87 | PPARG (0.65) | FAAHFABP3ALDH1A1PPARGKDM4E | |
| SCHEMBL28633229 | 0.87 | PPARG (0.65) | FAAHFABP3ALDH1A1PPARGKDM4E | |
| SCHEMBL28957396 | 0.85 | PPARG (0.64) | FABP3ALDH1A1PPARGKDM4EF7 | |
| SCHEMBL14166943 | 0.85 | ALDH1A1 (0.60) | FABP3ALDH1A1PPARGKDM4EF7 | |
| SCHEMBL3316574 | 0.84 | PPARG (0.59) | FABP3ALDH1A1PPARGKDM4EF7 | |
| SCHEMBL1117321 | 0.84 | ALDH1A1 (0.50) | FAAHALDH1A1PPARDFFAR1LMNA | |
| SCHEMBL1117357 | 0.84 | ALDH1A1 (0.50) | FAAHALDH1A1PPARDFFAR1LMNA | |
| SCHEMBL1117320 | 0.84 | ALDH1A1 (0.50) | FAAHALDH1A1PPARDFFAR1LMNA | |
| SCHEMBL1117361 | 0.84 | ALDH1A1 (0.50) | FAAHALDH1A1PPARDFFAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2743265-B1 | Improved amino lipids and methods for the delivery of nucleic acids | ARBUTUS BIOPHARMA CORP (CA) | 2017-03-15 | — | — | EP | disclosed |